Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

Refractive errors, in particular myopia, are a leading cause of morbidity and disability world-wide. Genetic investigation can improve understanding of the molecular mechanisms underlying abnormal eye development and impaired vision. We conducted a meta-analysis of genome-wide association studies in...

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Detaylı Bibliyografya
Yayımlandı:Nat Genet
Asıl Yazarlar: Hysi, Pirro G., Choquet, Hélène, Khawaja, Anthony P., Wojciechowski, Robert, Tedja, Milly S, Yin, Jie, Simcoe, Mark J., Patasova, Karina, Mahroo, Omar A., Thai, Khanh K, Cumberland, Phillippa M, Melles, Ronald B., Verhoeven, Virginie J.M., Vitart, Veronique, Segre, Ayellet, Stone, Richard A., Wareham, Nick, Hewitt, Alex W, Mackey, David A, Klaver, Caroline CW, MacGregor, Stuart, Khaw, Peng T., Foster, Paul J., Guggenheim, Jeremy A., Rahi, Jugnoo S, Jorgenson, Eric, Hammond, Christopher J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145443/
https://ncbi.nlm.nih.gov/pubmed/32231278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0599-0
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