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Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer

Nevirapine has been proved to be effective in inducing re-differentiation and suppressing tumor growth in several tumor cells. This study aims to investigate the therapeutic potential of nevirapine in dedifferentiated thyroid cancer (DeTC), which refractory to radioiodine treatment and the underlyin...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Shang, Hongxia, Zhao, Junyu, Yao, Jinming, Wang, Huanjun, Dong, Jianjun, Liao, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145398/
https://ncbi.nlm.nih.gov/pubmed/32300552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00404
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