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Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein–Ligand Interaction Studies

[Image: see text] In modern biochemistry, protein stability and ligand interactions are of high interest. These properties are often studied with methods requiring labeled biomolecules, as the existing methods utilizing luminescent external probes suffer from low sensitivity. Currently available lab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Vuorinen, Emmiliisa, Valtonen, Salla, Eskonen, Ville, Kariniemi, Taru, Jakovleva, Jelena, Kopra, Kari, Härmä, Harri
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145280/
https://ncbi.nlm.nih.gov/pubmed/32013400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b05712
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