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Enhancer occlusion transcripts regulate the activity of human enhancer domains via transcriptional interference: a computational perspective

Analysis of ENCODE long RNA-Seq and ChIP-seq (Chromatin Immunoprecipitation Sequencing) datasets for HepG2 and HeLa cell lines uncovered 1647 and 1958 transcripts that interfere with transcription factor binding to human enhancer domains. TFBSs (Transcription Factor Binding Sites) intersected by the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Pande, Amit, Makalowski, Wojciech, Brosius, Jürgen, Raabe, Carsten A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144904/
https://ncbi.nlm.nih.gov/pubmed/32133533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa026
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