Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts

We aimed to investigate the involvement of macroautophagy/autophagy in autoimmunity in rheumatoid arthritis (RA) through citrullination of VIM (vimentin) and its interaction with MHC class II in synovial fibroblasts (SFs). The cell surface expression of MHC class II and B7 costimulatory molecules on...

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Veröffentlicht in:Autophagy
Hauptverfasser: Sugawara, Eri, Kato, Masaru, Kudo, Yuki, Lee, Wenshi, Hisada, Ryo, Fujieda, Yuichiro, Oku, Kenji, Bohgaki, Toshiyuki, Amengual, Olga, Yasuda, Shinsuke, Onodera, Tomohiro, Hatakeyama, Shigetsugu, Atsumi, Tatsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144877/
https://ncbi.nlm.nih.gov/pubmed/31486697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1664144
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