Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

Every day, megakaryocytes produce billions of platelets that circulate for several days and eventually are cleared by the liver. The exact removal mechanism, however, remains unclear. Loss of sialic acid residues is thought to feature in the aging and clearance of platelets. Using state-of-the-art s...

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Vydáno v:J Exp Med
Hlavní autoři: Deppermann, Carsten, Kratofil, Rachel M., Peiseler, Moritz, David, Bruna A., Zindel, Joel, Castanheira, Fernanda Vargas E Silva, van der Wal, Fardau, Carestia, Agostina, Jenne, Craig N., Marth, Jamey D., Kubes, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144524/
https://ncbi.nlm.nih.gov/pubmed/31978220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190723
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