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Antiproliferative chromone derivatives induce K562 cell death through endogenous and exogenous pathways

A series of furoxan derivatives of chromone were prepared. The antiproliferative activities were tested against five cancer cell lines HepG2, MCF-7, HCT-116, B16, and K562, and two normal human cell lines L-02 and PBMCs. Among them, compound 15a exhibited the most potent antiproliferative activity....

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Jiao, Runwei, Xu, Fanxing, Huang, Xiaofang, Li, Haonan, Liu, Weiwei, Cao, Hao, Zang, Linghe, Li, Zhanlin, Hua, Huiming, Li, Dahong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144234/
https://ncbi.nlm.nih.gov/pubmed/32183548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1740696
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