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A Halogen Bonding Perspective on Iodothyronine Deiodinase Activity
Iodothyronine deiodinases (Dios) are involved in the regioselective removal of iodine from thyroid hormones (THs). Deiodination is essential to maintain TH homeostasis, and disruption can have detrimental effects. Halogen bonding (XB) to the selenium of the selenocysteine (Sec) residue in the Dio ac...
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| Pubblicato in: | Molecules |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144113/ https://ncbi.nlm.nih.gov/pubmed/32183289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061328 |
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