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A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466

In recent years, there has been a revival of interest in phenotypic-based drug discovery (PDD) due to target-based drug discovery (TDD) falling below expectations. Both PDD and TDD have their unique advantages and should be used as complementary methods in drug discovery. The PhenoTarget approach co...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Xie, Yan, Feng, Yunjiang, Di Capua, Angela, Mak, Tin, Buchko, Garry W., Myler, Peter J., Liu, Miaomiao, Quinn, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7143284/
https://ncbi.nlm.nih.gov/pubmed/32150903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18030149
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