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RHΔgra17Δnpt1 Strain of Toxoplasma gondii Elicits Protective Immunity Against Acute, Chronic and Congenital Toxoplasmosis in Mice

In the present study, a dense granule protein 17 (gra17) and novel putative transporter (npt1) double deletion mutant of Toxoplasma gondii RH strain was engineered. The protective efficacy of vaccination using RHΔgra17Δnpt1 tachyzoites against acute, chronic, and congenital toxoplasmosis was studied...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Liang, Qin-Li, Sun, Li-Xiu, Elsheikha, Hany M., Cao, Xue-Zhen, Nie, Lan-Bi, Li, Ting-Ting, Li, Tao-Shan, Zhu, Xing-Quan, Wang, Jin-Lei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142655/
https://ncbi.nlm.nih.gov/pubmed/32121619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8030352
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