Heat Shock Protein 70 Protects the Heart from Ischemia/Reperfusion Injury through Inhibition of p38 MAPK Signaling

BACKGROUND: Heat shock protein 70 (Hsp70) has been shown to exert cardioprotection. Intracellular calcium ([Ca(2+)](i)) overload induced by p38 mitogen-activated protein kinase (p38 MAPK) activation contributes to cardiac ischemia/reperfusion (I/R) injury. However, whether Hsp70 interacts with p38 M...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Song, Nan, Ma, Jiao, Meng, Xiao-wen, Liu, Hong, Wang, Hui, Song, Shao-yong, Chen, Qing-cai, Liu, Hua-yue, Zhang, Juan, Peng, Ke, Ji, Fu-hai
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142395/
https://ncbi.nlm.nih.gov/pubmed/32308802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3908641
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