The use of missing values in proteomic data-independent acquisition mass spectrometry to enable disease activity discrimination

MOTIVATION: Data-independent acquisition mass spectrometry allows for comprehensive peptide detection and relative quantification than standard data-dependent approaches. While less prone to missing values, these still exist. Current approaches for handling the so-called missingness have challenges....

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Vydáno v:Bioinformatics
Hlavní autoři: McGurk, Kathryn A, Dagliati, Arianna, Chiasserini, Davide, Lee, Dave, Plant, Darren, Baricevic-Jones, Ivona, Kelsall, Janet, Eineman, Rachael, Reed, Rachel, Geary, Bethany, Unwin, Richard D, Nicolaou, Anna, Keavney, Bernard D, Barton, Anne, Whetton, Anthony D, Geifman, Nophar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Original Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141869/
https://ncbi.nlm.nih.gov/pubmed/31790148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz898
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