Cocoa to Improve Walking Performance in Older People With Peripheral Artery Disease: The Cocoa-Pad Pilot Randomized Clinical Trial

RATIONALE: Cocoa and its major flavanol component, epicatechin, have therapeutic properties that may improve limb perfusion and increase calf muscle mitochondrial activity in people with lower extremity peripheral artery disease (PAD). OBJECTIVE: In a phase II randomized clinical trial, to assess wh...

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Veröffentlicht in:Circ Res
Hauptverfasser: McDermott, Mary M., Criqui, Michael H., Domanchuk, Kathryn, Ferrucci, Luigi, Guralnik, Jack M., Kibbe, Melina R., Kosmac, Kate, Kramer, Christopher M., Leeuwenburgh, Christiaan, Li, Lingyu, Lloyd-Jones, Donald, Peterson, Charlotte A., Polonsky, Tamar S., Stein, James H., Sufit, Robert, Van Horn, Linda, Villarreal, Francisco, Zhang, Dongxue, Zhao, Lihui, Tian, Lu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141749/
https://ncbi.nlm.nih.gov/pubmed/32078436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.315600
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