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The Switch from NF-YAl to NF-YAs Isoform Impairs Myotubes Formation
NF-YA, the regulatory subunit of the trimeric transcription factor (TF) NF-Y, is regulated by alternative splicing (AS) generating two major isoforms, “long” (NF-YAl) and “short” (NF-YAs). Muscle cells express NF-YAl. We ablated exon 3 in mouse C2C12 cells by a four-guide CRISPR/Cas9n strategy, obta...
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| 出版年: | Cells |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7140862/ https://ncbi.nlm.nih.gov/pubmed/32214056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030789 |
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