STAT3 Inhibitor ODZ10117 Suppresses Glioblastoma Malignancy and Prolongs Survival in a Glioblastoma Xenograft Model

Constitutively activated STAT3 plays an essential role in the initiation, progression, maintenance, malignancy, and drug resistance of cancer, including glioblastoma, suggesting that STAT3 is a potential therapeutic target for cancer therapy. We recently identified ODZ10117 as a small molecule inhib...

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Veröffentlicht in:Cells
Hauptverfasser: Kim, Byung-Hak, Lee, Haeri, Park, Cheol Gyu, Jeong, Ae Jin, Lee, Song-Hee, Noh, Kum Hee, Park, Jong Bae, Lee, Chung-Gi, Paek, Sun Ha, Kim, Hyunggee, Ye, Sang-Kyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140655/
https://ncbi.nlm.nih.gov/pubmed/32183406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030722
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