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GSK3β: A Master Player in Depressive Disorder Pathogenesis and Treatment Responsiveness
Glycogen synthase kinase 3β (GSK3β), originally described as a negative regulator of glycogen synthesis, is a molecular hub linking numerous signaling pathways in a cell. Specific GSK3β inhibitors have anti-depressant effects and reduce depressive-like behavior in animal models of depression. Theref...
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| Published in: | Cells |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7140610/ https://ncbi.nlm.nih.gov/pubmed/32188010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030727 |
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