Empagliflozin reduces vascular damage and cognitive impairment in a mixed murine model of Alzheimer’s disease and type 2 diabetes

BACKGROUND: Both Alzheimer’s disease (AD) and type 2 diabetes (T2D) share common pathological features including inflammation, insulin signaling alterations, or vascular damage. AD has no successful treatment, and the close relationship between both diseases supports the study of antidiabetic drugs...

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Veröffentlicht in:Alzheimers Res Ther
Hauptverfasser: Hierro-Bujalance, Carmen, Infante-Garcia, Carmen, del Marco, Angel, Herrera, Marta, Carranza-Naval, Maria Jose, Suarez, Javier, Alves-Martinez, Pilar, Lubian-Lopez, Simon, Garcia-Alloza, Monica
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140573/
https://ncbi.nlm.nih.gov/pubmed/32264944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00607-4
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