FAK Deficiency in Bone Marrow Stromal Cells Alters Their Homeostasis and Drives Abnormal Proliferation and Differentiation of Haematopoietic Stem Cells

Emerging evidence indicates that in myelodysplastic syndromes (MDS), the bone marrow (BM) microenvironment may also contribute to the ineffective, malignant haematopoiesis in addition to the intrinsic abnormalities of haematopoietic stem precursor cells (HSPCs). The BM microenvironment influences ma...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Wu, Yuenv, Campos, Lydia, Daguenet, Elisabeth, He, Zhiguo, Picot, Tiphanie, Tavernier-Tardy, Emmanuelle, Soglu, Gilbert, Guyotat, Denis, Aanei, Carmen-Mariana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140540/
https://ncbi.nlm.nih.gov/pubmed/32155953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030646
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