The Drosophila RNA Helicase Belle (DDX3) Non-Autonomously Suppresses Germline Tumorigenesis Via Regulation of a Specific mRNA Set

DDX3 subfamily DEAD-box RNA helicases are essential developmental regulators of RNA metabolism in eukaryotes. belle, the single DDX3 ortholog in Drosophila, is required for fly viability, fertility, and germline stem cell maintenance. Belle is involved both in translational activation and repression...

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Pubblicato in:Cells
Autori principali: Kotov, Alexei A., Godneeva, Baira K., Olenkina, Oxana M., Adashev, Vladimir E., Trostnikov, Mikhail V., Olenina, Ludmila V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140462/
https://ncbi.nlm.nih.gov/pubmed/32111103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030550
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