ATM-Deficient Cancers Provide New Opportunities for Precision Oncology

Poly-ADP ribose polymerase (PARP) inhibitors are currently used in the treatment of several cancers carrying mutations in the breast and ovarian cancer susceptibility genes BRCA1 and BRCA2, with many more potential applications under study and in clinical trials. Here, we discuss the potential for e...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Jette, Nicholas R., Kumar, Mehul, Radhamani, Suraj, Arthur, Greydon, Goutam, Siddhartha, Yip, Steven, Kolinsky, Michael, Williams, Gareth J., Bose, Pinaki, Lees-Miller, Susan P.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140103/
https://ncbi.nlm.nih.gov/pubmed/32183301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030687
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