Analysis of Dual Class I Histone Deacetylase and Lysine Demethylase Inhibitor Domatinostat (4SC-202) on Growth and Cellular and Genomic Landscape of Atypical Teratoid/Rhabdoid

Central nervous system atypical teratoid/rhabdoid tumors (ATRTs) are rare and aggressive tumors with a very poor prognosis. Current treatments for ATRT include resection of the tumor, followed by systemic chemotherapy and radiation therapy, which have toxic side effects for young children. Gene expr...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Hoffman, Mariah M., Zylla, Jessica S., Bhattacharya, Somshuvra, Calar, Kristin, Hartman, Timothy W., Bhardwaj, Ratan D., Miskimins, W. Keith, de la Puente, Pilar, Gnimpieba, Etienne Z., Messerli, Shanta M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140080/
https://ncbi.nlm.nih.gov/pubmed/32210076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030756
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