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Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface
Down regulation of the major histocompatibility class (MHC) I pathway plays an important role in tumour development, and can be achieved by suppression of HLA expression or mutations in the MHC peptide-binding pocket. The peptide-loading complex (PLC) loads peptides on the MHC-I molecule in a dynami...
Gardado en:
| Publicado en: | Cancers (Basel) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7140079/ https://ncbi.nlm.nih.gov/pubmed/32244998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030737 |
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