Upregulation of Protein Synthesis and Proteasome Degradation Confers Sensitivity to Proteasome Inhibitor Bortezomib in Myc-Atypical Teratoid/Rhabdoid Tumors

Atypical teratoid rhabdoid tumors (ATRTs) are among the most malignant brain tumors in early childhood and remain incurable. Myc-ATRT is driven by the Myc oncogene, which directly controls the intracellular protein synthesis rate. Proteasome inhibitor bortezomib (BTZ) was approved by the Food and Dr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Tran, Huy Minh, Wu, Kuo-Sheng, Sung, Shian-Ying, Changou, Chun Austin, Hsieh, Tsung-Han, Liu, Yun-Ru, Liu, Yen-Lin, Tsai, Min-Lan, Lee, Hsin-Lun, Hsieh, Kevin Li-Chun, Huang, Wen-Chang, Liang, Muh-Lii, Chen, Hsin-Hung, Lee, Yi-Yen, Lin, Shih-Chieh, Ho, Donald Ming-Tak, Chang, Feng-Chi, Chao, Meng-En, Chen, Wan, Chu, Shing-Shung, Yu, Alice L., Yen, Yun, Chang, Che-Chang, Wong, Tai-Tong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140067/
https://ncbi.nlm.nih.gov/pubmed/32235770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030752
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