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Comparative Molecular Analysis of Cancer Behavior Cultured In Vitro, In Vivo, and Ex Vivo

Current pre-clinical models of cancer fail to recapitulate the cancer cell behavior in primary tumors primarily because of the lack of a deeper understanding of the effects that the microenvironment has on cancer cell phenotype. Transcriptomic profiling of 4T1 murine mammary carcinoma cells from 2D...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Hum, Nicholas R., Sebastian, Aimy, Gilmore, Sean F., He, Wei, Martin, Kelly A., Hinckley, Aubree, Dubbin, Karen R., Moya, Monica L., Wheeler, Elizabeth K., Coleman, Matthew A., Loots, Gabriela G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140030/
https://ncbi.nlm.nih.gov/pubmed/32183351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030690
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