Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome

Chronic rejection is the major leading cause of morbidity and mortality after lung transplantation. Bronchiolitis obliterans syndrome (BOS), a fibroproliferative disorder of the small airways, is the main manifestation of chronic lung allograft rejection. We investigated, using transgenic mice, the...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: D’Amico, Ramona, Fusco, Roberta, Cordaro, Marika, Siracusa, Rosalba, Peritore, Alessio Filippo, Gugliandolo, Enrico, Crupi, Rosalia, Scuto, Maria, Cuzzocrea, Salvatore, Di Paola, Rosanna, Impellizzeri, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139667/
https://ncbi.nlm.nih.gov/pubmed/32244997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21062144
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