The Roles of Cyclin-Dependent Kinases in Cell-Cycle Progression and Therapeutic Strategies in Human Breast Cancer

Cyclin-dependent kinases (CDKs) are serine/threonine kinases whose catalytic activities are regulated by interactions with cyclins and CDK inhibitors (CKIs). CDKs are key regulatory enzymes involved in cell proliferation through regulating cell-cycle checkpoints and transcriptional events in respons...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Ding, Lei, Cao, Jiaqi, Lin, Wen, Chen, Hongjian, Xiong, Xianhui, Ao, Hongshun, Yu, Min, Lin, Jie, Cui, Qinghua
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139603/
https://ncbi.nlm.nih.gov/pubmed/32183020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21061960
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