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Recovery of Adrenal Insufficiency Is Frequent After Adjuvant Mitotane Therapy in Patients with Adrenocortical Carcinoma

Mitotane is a steroidogenesis inhibitor and adrenolytic drug used for treatment of adrenocortical cancer (ACC). Mitotane therapy causes adrenal insufficiency requiring glucocorticoid replacement in all patients. However, it is unclear whether chronic therapy with mitotane induces complete destructio...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Poirier, Jonathan, Gagnon, Nadia, Terzolo, Massimo, Puglisi, Soraya, Ghorayeb, Nada El, Calabrese, Anna, Lacroix, André, Bourdeau, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139486/
https://ncbi.nlm.nih.gov/pubmed/32164326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030639
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