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The influence of ABCG2 polymorphism on erlotinib efflux in the K562 cell line

Single nucleotide polymorphisms (SNPs) in the gene for multidrug resistance protein ABCG2, an erlotinib transporter, is a possible contributor to the interindividual variation observed in erlotinib pharmacokinetics and toxicity. Therefore, the aim was to study erlotinib efflux by ABCG2 wild‐type (wt...

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Publicat a:Pharmacol Res Perspect
Autors principals: Svedberg, Anna, Jacobs, Lianne, Vikingsson, Svante, Gréen, Henrik
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138917/
https://ncbi.nlm.nih.gov/pubmed/32266784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.581
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