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Integrative analysis of DNA methylation and gene expression reveals distinct hepatocellular carcinoma subtypes with therapeutic implications

We aimed to develop an HCC classification model based on the integrated gene expression and methylation data of methylation-driven genes. Genome, methylome, transcriptome, proteomics and clinical data of 369 HCC patients from The Cancer Genome Atlas Network were retrieved and analyzed. Consensus clu...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Huang, Xiaowen, Yang, Chen, Wang, Jilin, Sun, Tiantian, Xiong, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138576/
https://ncbi.nlm.nih.gov/pubmed/32201399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102923
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