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MicroRNA-325-3p prevents sevoflurane-induced learning and memory impairment by inhibiting Nupr1 and C/EBPβ/IGFBP5 signaling in rats

Endoplasmic reticulum stress-induced neuronal apoptosis contributes to neurotoxicity observed after sevoflurane exposure. However, the molecular mechanism underlying the resulting learning and memory impairments remains unknown. Here, we investigated the roles of miR-325-3p and Nupr1 in sevoflurane-...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Xu, Lili, Xu, Qi, Xu, Fang, Zhang, Wenxin, Chen, Qing, Wu, Hui, Chen, Xinzhong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138556/
https://ncbi.nlm.nih.gov/pubmed/32191629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102942
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