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Prolyl 4‐hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas, and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls

Melanoma is an unpredictable, highly metastatic malignancy, and treatment of advanced melanoma remains challenging. Novel molecular markers based on the alterations in gene expression and the molecular pathways activated or deactivated during melanoma progression are needed for predicting the course...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Eriksson, Johanna, Le Joncour, Vadim, Jahkola, Tiina, Juteau, Susanna, Laakkonen, Pirjo, Saksela, Olli, Hölttä, Erkki
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138405/
https://ncbi.nlm.nih.gov/pubmed/32053263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12649
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