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Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus

BACKGROUND: Metformin is an oral anti‐hyperglycemic agent that has been shown to reduce total mortality compared to other anti‐hyperglycemic agents, in the treatment of type 2 diabetes mellitus. Metformin, however, is thought to increase the risk of lactic acidosis, and has been considered to be con...

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發表在:Cochrane Database Syst Rev
Main Authors: Salpeter, Shelley R, Greyber, Elizabeth, Pasternak, Gary A, Salpeter, Edwin E
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Ltd 2010
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138050/
https://ncbi.nlm.nih.gov/pubmed/20393934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD002967.pub4
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