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Beta-adrenergic agonist protects retinal pigment epithelium against hydroxycholoroquine toxicity via cAMP-PKA signal pathway

AIM: To test our hypothesis that activation of protein kinase A (PKA) signal pathway by β-adrenergic agonist plays an important role in the protecting of cultured retinal pigment epithelial (RPE) cells against the hydroxychloroquine (HCQ) toxicity. METHODS: Cultured human RPE cells were treated with...

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Detalles Bibliográficos
Publicado en:Int J Ophthalmol
Main Authors: Zhang, Ruihua, Hu, Dan-Ning, Rosen, Richard
Formato: Artigo
Idioma:Inglês
Publicado: International Journal of Ophthalmology Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137693/
https://ncbi.nlm.nih.gov/pubmed/32399404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2020.04.04
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