Adaptive RSK‐EphA2‐GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer

Metastatic cancers commonly activate adaptive chemotherapy resistance, attributed to both microenvironment‐dependent phenotypic plasticity and genetic characteristics of cancer cells. However, the contribution of chemotherapy itself to the non‐genetic resistance mechanisms was long neglected. Using...

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Détails bibliographiques
Publié dans:EMBO Mol Med
Auteurs principaux: Moyano‐Galceran, Lidia, Pietilä, Elina A, Turunen, S Pauliina, Corvigno, Sara, Hjerpe, Elisabet, Bulanova, Daria, Joneborg, Ulrika, Alkasalias, Twana, Miki, Yuichiro, Yashiro, Masakazu, Chernenko, Anastasiya, Jukonen, Joonas, Singh, Madhurendra, Dahlstrand, Hanna, Carlson, Joseph W, Lehti, Kaisa
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136956/
https://ncbi.nlm.nih.gov/pubmed/32115889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911177
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