A 23 bp cyp51A Promoter Deletion Associated With Voriconazole Resistance in Clinical and Environmental Isolates of Neocosmospora keratoplastica

In the fungal pathogen Aspergillus fumigatus, resistance to azole antifungals is often linked to mutations in CYP51A, a gene that encodes the azole antifungal drug target lanosterol 14α-demethylase. The aim of this study was to investigate whether similar changes could be associated with azole resis...

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Publicat a:Front Microbiol
Autors principals: James, Jasper Elvin, Lamping, Erwin, Santhanam, Jacinta, Milne, Trudy Jane, Abd Razak, Mohd Fuat, Zakaria, Latiffah, Cannon, Richard David
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136401/
https://ncbi.nlm.nih.gov/pubmed/32296397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00272
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