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Prolyl Isomerase Pin1 in Human Cancer: Function, Mechanism, and Significance

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) is an evolutionally conserved and unique enzyme that specifically catalyzes the cis-trans isomerization of phosphorylated serine/threonine-proline (pSer/Thr-Pro) motif and, subsequently, induces the conformational change of its substrates...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Pu, Wenchen, Zheng, Yuanyuan, Peng, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136398/
https://ncbi.nlm.nih.gov/pubmed/32296699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00168
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