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Interpretation of HDX Data by Maximum-Entropy Reweighting of Simulated Structural Ensembles
Hydrogen-deuterium exchange combined with mass spectrometry (HDX-MS) is a widely applied biophysical technique that probes the structure and dynamics of biomolecules without the need for site-directed modifications or bio-orthogonal labels. The mechanistic interpretation of HDX data, however, is oft...
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| Publicado en: | Biophys J |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Biophysical Society
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7136279/ https://ncbi.nlm.nih.gov/pubmed/32105651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.02.005 |
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