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Development and In Vitro Evaluation of Stearic Acid Phosphotyrosine Amide as New Excipient for Zeta Potential Changing Self-Emulsifying Drug Delivery Systems

ABSTRACT: PURPOSE: Development of zeta potential changing SEDDS containing newly synthesized derivative stearic acid phosphotyrosine amide. METHODS: Stearoyl chloride was conjugated with phosphotyrosine, which is substrate for the brush border enzyme intestinal alkaline phosphate. The synthesized de...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Prüfert, Felix, Fischer, Franz, Leichner, Christina, Zaichik, Sergey, Bernkop-Schnürch, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136179/
https://ncbi.nlm.nih.gov/pubmed/32253523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02802-2
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