A two-part phase I study to establish and compare the safety and local tolerability of two nasal formulations of XF-73 for decolonization of Staphylococcus aureus: A previously investigated 0.5 mg/g viscosified gel formulation versus a modified formulation

OBJECTIVES: There is conflicting data on the success of mupirocin as an effective decolonizing regimen for Staphylococcus aureus (SA) carriage, in part due to increasing drug resistance. This multi-center, randomized, open-label, prospective phase 1 study compared the safety and local tolerability o...

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Vydáno v:J Glob Antimicrob Resist
Hlavní autoři: Yendewa, George A., Griffiss, J. McLeod, Jacobs, Michael R., Winkle, Peter, Gray, Wesley A., Proskin, Howard M., O’Riordan, Mary Ann, Fulton, Scott A., Salata, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136135/
https://ncbi.nlm.nih.gov/pubmed/31600598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgar.2019.09.017
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