Genomic and serologic characterization of enterovirus A71 brainstem encephalitis

OBJECTIVE: In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the periphery but rarely in CSF. Metagenomic next-generation sequencing (mNGS) and CSF pan-viral serology (VirScan) were deployed to enhance...

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Publicado en:Neurol Neuroimmunol Neuroinflamm
Main Authors: Leon, Kristoffer E., Schubert, Ryan D., Casas-Alba, Didac, Hawes, Isobel A., Ramachandran, Prashanth S., Ramesh, Akshaya, Pak, John E., Wu, Wesley, Cheung, Carly K., Crawford, Emily D., Khan, Lillian M., Launes, Cristian, Sample, Hannah A., Zorn, Kelsey C., Cabrerizo, Maria, Valero-Rello, Ana, Langelier, Charles, Muñoz-Almagro, Carmen, DeRisi, Joseph L., Wilson, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136061/
https://ncbi.nlm.nih.gov/pubmed/32139440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000703
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