Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet–fed mice

Nonalcoholic fatty liver disease is a rapidly rising problem in the 21st century and is a leading cause of chronic liver disease that can lead to end-stage liver diseases, including cirrhosis and hepatocellular cancer. Despite this rising epidemic, no pharmacological treatment has yet been establish...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Takahashi, Shogo, Luo, Yuhuan, Ranjit, Suman, Xie, Cen, Libby, Andrew E., Orlicky, David J., Dvornikov, Alexander, Wang, Xiaoxin X., Myakala, Komuraiah, Jones, Bryce A., Bhasin, Kanchan, Wang, Dong, McManaman, James L., Krausz, Kristopher W., Gratton, Enrico, Ir, Diana, Robertson, Charles E., Frank, Daniel N., Gonzalez, Frank J., Levi, Moshe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135973/
https://ncbi.nlm.nih.gov/pubmed/32075905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011913
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