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Ewing sarcoma with FEV gene rearrangements is a rare subset with predilection for extra-skeletal locations and aggressive behavior
The molecular hallmark of Ewing sarcoma (ES) is a fusion involving the EWSR1 gene and a member of the ETS family of transcription factors. EWSR1-FLI1 is the most common variant, occurring in 90% of cases, followed by EWSR1-ERG. In rare cases the FUS gene can substitute for EWSR1 in these fusions. On...
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| Publicat a: | Genes Chromosomes Cancer |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7135932/ https://ncbi.nlm.nih.gov/pubmed/31756779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22828 |
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