AKT2 deficiency impairs formation of the BCR signalosome

BACKGROUND: AKT2 is one of the key molecules that involves in the insulin-induced signaling and the development of cancer. In B cells, the function of AKT2 is unclear. METHODS: In this study, we used AKT2 knockout mice model to study the role of AKT2 in BCR signaling and B cell differentiation. RESU...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Du, Zuochen, Yang, Di, Zhang, Yongjie, Xuan, Xingtian, Li, Han, Hu, Leling, Ruan, Changshun, Li, Liling, Chen, Anwei, Deng, Liang, Chen, Yan, Xie, Jingwen, Westerberg, Lisa S., Huang, Lu, Liu, Chaohong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7133013/
https://ncbi.nlm.nih.gov/pubmed/32252758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00534-9
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