Effectiveness of TOcilizumab in comparison to Prednisone In Rheumatoid Arthritis patients with insufficient response to disease-modifying antirheumatic drugs (TOPIRA): study protocol for a pragmatic trial

BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, predominantly affecting joints, which is initially treated with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs). In RA patients with insufficient response to csDMARDs, the addition of predniso...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: van der Leeuw, Matthijs S., Welsing, Paco M. J., de Hair, Maria J. H., Jacobs, Johannes W. G., Marijnissen, Anne C. A., Linn-Rasker, Suzanne P., Fodili, Faouzia, Bos, Reinhard, Tekstra, Janneke, van Laar, Jacob M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7133012/
https://ncbi.nlm.nih.gov/pubmed/32248829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04260-y
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