NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture

Neutrophil extracellular traps (NETs) are web-like DNA structures decorated with histones and cytotoxic proteins that are released by activated neutrophils to trap and neutralize pathogens during the innate immune response, but also form in and exacerbate sterile inflammation. Peptidylarginine deimi...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Thiam, Hawa Racine, Wong, Siu Ling, Qiu, Rong, Kittisopikul, Mark, Vahabikashi, Amir, Goldman, Anne E., Goldman, Robert D., Wagner, Denisa D., Waterman, Clare M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132277/
https://ncbi.nlm.nih.gov/pubmed/32170015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909546117
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