Diterpene Ginkgolides Exert an Antidepressant Effect Through the NT3-TrkA and Ras-MAPK Pathways

BACKGROUND: Depression is a highly prevalent mental illness that severely impacts the quality of life of affected individuals. Our recent studies demonstrated that diterpene ginkgolides (DG) have antidepressant effects in mice. However, the underlying molecular mechanisms remained much unclear. METH...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wang, Ting, Bai, Shunjie, Wang, Wei, Chen, Zhi, Chen, Jianjun, Liang, Zihong, Qi, Xunzhong, Shen, Hailan, Xie, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132272/
https://ncbi.nlm.nih.gov/pubmed/32308365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S229145
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