Optogenetic control of mitochondrial protonmotive force to impact cellular stress resistance

Mitochondrial respiration generates an electrochemical proton gradient across the mitochondrial inner membrane called protonmotive force (PMF) to drive diverse functions and synthesize ATP. Current techniques to manipulate the PMF are limited to its dissipation; yet, there is no precise and reversib...

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Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Berry, Brandon J, Trewin, Adam J, Milliken, Alexander S, Baldzizhar, Aksana, Amitrano, Andrea M, Lim, Yunki, Kim, Minsoo, Wojtovich, Andrew P
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132214/
https://ncbi.nlm.nih.gov/pubmed/32043300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949113
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