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Optogenetic control of mitochondrial protonmotive force to impact cellular stress resistance

Mitochondrial respiration generates an electrochemical proton gradient across the mitochondrial inner membrane called protonmotive force (PMF) to drive diverse functions and synthesize ATP. Current techniques to manipulate the PMF are limited to its dissipation; yet, there is no precise and reversib...

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Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: Berry, Brandon J, Trewin, Adam J, Milliken, Alexander S, Baldzizhar, Aksana, Amitrano, Andrea M, Lim, Yunki, Kim, Minsoo, Wojtovich, Andrew P
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132214/
https://ncbi.nlm.nih.gov/pubmed/32043300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949113
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