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Optogenetic control of mitochondrial protonmotive force to impact cellular stress resistance

Mitochondrial respiration generates an electrochemical proton gradient across the mitochondrial inner membrane called protonmotive force (PMF) to drive diverse functions and synthesize ATP. Current techniques to manipulate the PMF are limited to its dissipation; yet, there is no precise and reversib...

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Publicat a:EMBO Rep
Autors principals: Berry, Brandon J, Trewin, Adam J, Milliken, Alexander S, Baldzizhar, Aksana, Amitrano, Andrea M, Lim, Yunki, Kim, Minsoo, Wojtovich, Andrew P
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132214/
https://ncbi.nlm.nih.gov/pubmed/32043300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949113
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