Intracellular processing of the N-terminal ORF 1a proteins of the coronavirus MHV-A59 requires multiple proteolytic events

Several polypeptide products of MHV-A59 ORF 1a were characterized in MHV-A59 infected DBT cells, using antisera directed against fusionn roteins encoded in the first 6.5 kb of ORF1a. These included the previously identified N-terminal ORF 1a product, p28, as well as 290-, 240-, and 50-kDa polypeptid...

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Publicado en:Virology
Main Authors: Denison, Mark R., Zoltick, Philip W., Hughes, Scott A., Giangreco, Bernadette, Olson, Ann L., Perlman, Stanley, Leibowitz, Julian L., Weiss, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado: Published by Elsevier Inc. 1992
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7130892/
https://ncbi.nlm.nih.gov/pubmed/1318604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0042-6822(92)90703-R
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