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Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus

The Spike (S) glycoprotein of coronaviruses (CoV) mediates viral entry into host cells. It contains two hydrophobic heptad repeat (HR) regions, denoted HRN and HRC, which oligomerize the S glycoprotein into a trimer in the native state and when activated collapse into a six-helix bundle structure dr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Struct Biol
Päätekijät: Tripet, Brian, Kao, Daniel J., Jeffers, Scott A., Holmes, Kathryn V., Hodges, Robert S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Inc. 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7129695/
https://ncbi.nlm.nih.gov/pubmed/16697221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2006.03.019
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