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206: Transcriptional signatures of pathogenesis and successful type I interferon and ribavirin therapy in a rhesus macaque model of MERS-CoV infection

A novel betacoronavirus, Middle East respiratory syndrome coronavirus (MERS-CoV), emerged on the Arabian Peninsula in 2012. MERS-CoV was found to produce severe respiratory illness with case-fatality rates near 50%, and may be transmitted person-to-person in instances of close physical contact, such...

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Detalhes bibliográficos
Publicado no:Cytokine
Main Authors: Rasmussen, Angela L., Falzarano, Darryl, de Wit, Emmie, Feldmann, Friederike, Okumura, Atsushi, Scott, Dana P., Brining, Douglas, Bushmaker, Trent, Martellaro, Cynthia, Benecke, Arndt G., Munster, Vincent J., Feldmann, Heinz, Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier Ltd. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128186/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.06.209
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